AICAR — Research Overview

Also known as: AICA Ribonucleotide, Acadesine, 5-AICAR

5-Aminoimidazole-4-carboxamide ribonucleotide — a cell-permeable nucleoside analog that activates AMP-activated protein kinase (AMPK), the cellular energy sensor. AICAR is studied as an exercise mimetic that increases mitochondrial biogenesis, fatty acid oxidation, and endurance capacity without physical exertion. Research interest spans metabolic disease, obesity, and longevity.

Back to Peptide Encyclopedia