SLU-PP-332 — Research Overview

Also known as: ERR agonist, SLU PP 332, Pan-ERR agonist

A potent agonist of estrogen-related receptors ERRα and ERRγ — orphan nuclear receptors that regulate mitochondrial biogenesis and oxidative metabolism. SLU-PP-332 is studied as an exercise mimetic that dramatically increases endurance, fat oxidation, and mitochondrial density in skeletal muscle without physical exertion, and shows protective effects in heart failure models.

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