SS-31 — Research Overview

Also known as: Elamipretide, Forzinity

A water-soluble, cell-permeable tetrapeptide that selectively targets cardiolipin on the inner mitochondrial membrane, stabilizing electron transport chain supercomplexes and reducing reactive oxygen species generation. In September 2025, the FDA granted accelerated approval to SS-31 under the brand name Forzinity as the first drug ever approved to directly target mitochondrial function.

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