Bioregulators

In these encyclopedia entries, bioregulators are tissue-focused peptides or peptide preparations studied for regulation of cellular activity. This directory is not limited to Khavinson-developed entries. Entries marked “Khavinson peptide” were developed by Prof. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology.

Entries are included when their stored classification identifies them as bioregulators, supported by stored entry text or a cited source. General supplements and antioxidants are not included simply because they are studied in longevity research.

21 encyclopedia entries

  • Bronchogen

    Khavinson peptide

    Bronchogen is a tetrapeptide bioregulator developed by Professor Vladimir Khavinson's team targeting bronchopulmonary tissue — specifically the bronchi and bronchioles.

  • Cardiogen

    Khavinson peptide

    Cardiogen is a tetrapeptide bioregulator developed by Professor Vladimir Khavinson targeting cardiac muscle tissue (myocardium).

  • Cartalax

    Khavinson peptide

    Cartalax is a tetrapeptide bioregulator developed by Professor Vladimir Khavinson targeting cartilage tissue — specifically articular cartilage and intervertebral disc cartilage.

  • Chonluten

    Khavinson peptide

    Chonluten is a synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Leu) developed by Professor Vladimir Khavinson and colleagues at the St.

  • Cortagen

    Khavinson peptide

    Cortagen is a synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Arg) developed by Professor Vladimir Khavinson and the St.

  • Cortexin

    Cortexin is a polypeptide neuropeptide complex derived from porcine (pig) cerebral cortex tissue, manufactured by Geropharm in Russia.

  • Epitalon (Epithalon)

    Khavinson peptide

    Epitalon, also spelled Epithalon, is a synthetic tetrapeptide (Ala-Glu-Asp-Gly, AEDG) based on the natural peptide Epithalamin, isolated from the pineal gland by Professor Vladimir Khavinson.

  • Livagen

    Khavinson peptide

    Livagen is a synthetic tetrapeptide bioregulator with the sequence Lys-Glu-Asp-Ala (KEDA) , developed at the St.

  • Ovagen

    Khavinson peptide

    Ovagen is a synthetic tripeptide bioregulator with the sequence Glu-Asp-Leu (EDL) , developed at the St.

  • Pancragen

    Khavinson peptide

    Pancragen is a tetrapeptide bioregulator developed by Professor Vladimir Khavinson targeting the pancreas — both its endocrine function (insulin and glucagon secretion from islets of Langerhans) and its exocrine function (digestive enzyme production from acinar cells).

  • Pielotax

    Khavinson peptide

    Pielotax is a tetrapeptide bioregulator developed by Professor Vladimir Khavinson targeting kidney (renal) tissue.

  • Pinealon

    Khavinson peptide

    Pinealon is a synthetic tripeptide (Glu-Asp-Arg) bioregulator developed by Professor Vladimir Khavinson specifically targeting brain tissue.

  • Prostamax

    Khavinson peptide

    Prostamax is a peptide bioregulator developed by Professor Vladimir Khavinson specifically targeting prostate tissue.

  • Testagen

    Khavinson peptide

    Testagen is a tetrapeptide bioregulator developed by Professor Vladimir Khavinson targeting testicular tissue — specifically the Leydig cells (testosterone-producing) and Sertoli cells (spermatogenesis-supporting) of the testis.

  • Thymalin

    Khavinson peptide

    Thymalin is a polypeptide preparation derived from bovine thymus gland through standardized extraction.

  • Thymogen

    Khavinson peptide

    Thymogen is a synthetic dipeptide bioregulator with the sequence Glu‑Trp (EW), originally isolated as one of the active short peptides within the thymus extract Thymalin and later synthesized as a defined molecule.

  • Thymulin

    Thymulin (formerly called Facteur Thymique Serique or FTS) is a nonapeptide — nine amino acids — produced and secreted exclusively by epithelial cells of the thymus gland.

  • Ventfort

    Khavinson peptide

    Ventfort is a vascular-specific peptide bioregulator containing a complex of low-molecular-weight peptides (≤10,000 Da) isolated from the aortic tissue of young calves (≤12 months).

  • Vesilute

    Khavinson peptide

    Vesilute is a synthetic tetrapeptide bioregulator developed by Professor Vladimir Khavinson’s group at the St.

  • Vesugen

    Khavinson peptide

    Vesugen is a tripeptide bioregulator (Lys-Glu-Asp) developed by Professor Vladimir Khavinson specifically targeting vascular endothelial tissue.

  • Vilon

    Khavinson peptide

    Vilon is a synthetic dipeptide bioregulator with sequence Lys-Glu (KE), originally isolated from thymus tissue and subsequently synthesized as a sequence-defined compound.

Frequently asked questions

What is a bioregulator?

In these encyclopedia entries, bioregulators are tissue-focused peptides or peptide preparations studied for regulation of cellular activity.

Which bioregulators were developed by Khavinson?

The stored Khavinson-flagged entries are Bronchogen, Cardiogen, Cartalax, Chonluten, Cortagen, Epitalon (Epithalon), Livagen, Ovagen, Pancragen, Pielotax, Pinealon, Prostamax, Testagen, Thymalin, Thymogen, Ventfort, Vesilute, Vesugen, Vilon. Their entry pages contain the stored development attribution and its sources.

Which entries are included in this directory?

Entries are included when their stored classification identifies them as bioregulators, supported by stored entry text or a cited source. General supplements and antioxidants are not included simply because they are studied in longevity research.

What is a Cytogen?

The synthetic category of bioregulator peptides, also called tissue-specific peptides. Cytogens are fully synthesized versions of the bioactive peptide sequences identified within natural tissue extracts. The stored Epitalon (Epithalon) entry describes a synthetic tetrapeptide.

What does Khavinson Peptides mean?

The informal collective name for the bioregulator peptides developed by Dr. Vladimir Khavinson and his research team at the St. Petersburg Institute of Bioregulation and Gerontology.

Is it Epitalon or Epithalon?

Epitalon and Epithalon are spellings of the same compound. Epitalon is the canonical name used here. Both refer to the Ala-Glu-Asp-Gly (AEDG) tetrapeptide.

Sources